Ocean acidification affects the expression of neuroplasticity and neuromodulation markers in seabream

A possible explanation for acidification-induced changes in fish behaviour is that acidification interferes with neurogenesis and modifies the plasticity of neuronal circuitry in the brain. We tested the effects on the olfactory system and brain of gilthead seabream (Sparus aurata) of four weeks’ exposure to OA. Olfactory epithelium (OE) morphology changed shortly after OA exposure and persisted over the four-weeks. Expression of genes related to olfactory transduction, neuronal excitability, synaptic plasticity, GABAergic innervation, and cell proliferation were unchanged in the OE and olfactory bulb (OB) after four weeks’ exposure. Short-term changes in the ionic content of plasma and extradural fluid (EDF) returned to control levels after four weeks exposure, except for [Cl-] which remained elevated. This suggests that, in general, there is an early physiological response to OA and by four weeks a new homeostatic status is achieved. However, expression of genes involved in proliferation, differentiation and survival of undifferentiated neurons were modified in the brain. In the same brain areas, expression of thyroid hormone signalling genes was altered suggesting modifications in the thyroid-system may be linked to the changes in neuroplasticity and neurogenesis. Overall, the results of the current study are consistent with and effect of OA on neuroplasticity.

Costa R. A., Olvera A., Power D. M. & Velez Z., 2022. Ocean acidification affects the expression of neuroplasticity and neuromodulation markers in seabream. Biology Open: bio.059073. doi: 10.1242/bio.059073. Article.


  • Reset

Subscribe

OA-ICC Highlights


%d bloggers like this: